Abstract: Cyclic peptides become attractive therapeutic candidates due to their diverse biological activities. However, existing deep learning-based sequence design models, such as ProteinMPNN, are ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

If you work with strings in your Python scripts and you're writing obscure logic to process them, then you need to look into ...

Abstract: Improving the ability to predict protein function can potentially facilitate research in the fields of drug discovery and precision medicine. Technically, the properties of proteins are ...

python-iso20022/ ├── .github/workflows # CI/CD workflows ├── python_iso20022/ # Top-level package directory │ ├── acmt/ # Example of a message set directory │ │ ├── acmt_001_001_08/ # Directory for a ...

ClickHouse-based cryptocurrency data collection with zero-gap guarantee. Optimized for bulk historical data via Binance public repository with persistent database storage and USDT-margined futures ...