Technologies at the Advanced Rodent Transgenics Laboratory include genome editing design and implementation and transgenic ...

Humanized mouse models are vital for studying human gene function, but fully replacing mouse genes with complete human ...

Scientists have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19. Scientists at La Jolla Institute for Immunology (LJI) have developed six ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...

This year could mark a turning point for one of science’s most familiar animals: the laboratory mouse. For decades, mice and ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...