Study has combined genome-wide data with plasma proteomics from a Ugandan cohort to map hundreds of genetic regulators of ...

Animal breeding has traditionally focused on improving mean trait performance; however, contemporary research increasingly highlights the significance of genetic variation not only in trait means but ...

Genetic variation in livestock is a critical area of research that underpins modern breeding practices and agricultural productivity. Differences in DNA sequences, including single nucleotide ...

Study: Signatures of transmission in within-host Mycobacterium tuberculosis complex variation: a retrospective genomic epidemiology study. Image Credit: Creativa Images/Shutterstock.com Reducing the ...

Detecting genetic variants associated with the variance of complex traits, that is, variance quantitative trait loci (vQTLs), can provide crucial insights into the interplay between genes and ...

PanMAN data structures compress pangenomes massively, encode evolutionary histories, and enable scalable analysis of millions of genomes.

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease caused by repetitive head impacts (RHI). However, individuals with similar RHI exposure have shown differing pathology, suggesting ...

Researchers have significantly expanded the catalogue of known human genetic variation. The resulting datasets, shared in two back-to-back publications in the journal Nature, constitute what may be ...

Even a single gene, reshuffled or regulated in new ways, can fuel repeated bursts of evolutionary innovation, according to a recent study of wheatear birds. A study was recently published in the ...

There are a number of C. trachomatis gene products that exhibit variability and may modulate disease severity (Figure 3). The major categories of variable chlamydial gene products and their roles in ...

Genetic inheritance may sound straightforward: One gene causes one trait or a specific illness. When doctors use genetics, it’s usually to try to identify a disease-causing gene to help guide ...