Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

Spatial transcriptomics and gene expression analysis represent a transformative approach in biomedical research, integrating the spatial context of tissues with high-resolution profiling of gene ...

This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.

For spatial biology to deliver on its potential, foundational aspects of the spatial analysis workflow need to be executed with precision. Here, Kalins Banerjee and Evan Keller explain the importance ...

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning. Understanding these spatial arrangements is important when ...

Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Illumina is raising the curtain on its upcoming entry into spatial transcriptomics, with tech designed to help researchers explore cellular behavior mapped across complex tissues. The announcement ...

The spatial genomics & transcriptomics market is expanding under the influence of factors including rising acceptance of spatial genomics and transcriptomics techniques for drug discovery and ...