Diverse high cognitive functions were supported by cellular circuits formed by billion neural cells in different cerebral cortex regions 1,2,3. High-resolution “cytoarchitectural atlas” of the human ...

Why do so many promising drugs fail? This article explores how spatial multiomics reveals hidden cell interactions, helping ...

Spatial transcriptomics technologies have fundamentally transformed our ability to map gene expression within complex tissues, providing unprecedented insights into cellular heterogeneity and tissue ...

【免费】第二届西部单细胞与空间组学论坛近日，武汉大学人民医院研究团队在期刊《Advanced Science》上发表了题为“Single-Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics”的研究论文，本研究开发了A ...

This illustration summarizes how integrated spatial transcriptomics, single-cell transcriptomics, single-cell epigenomics, and spatial epigenomics enable multi-dimensional profiling of the tumor ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder ...

Technological development is key to improving the way hematologic cancer is diagnosed and treated. With this vision, the Josep Carreras Leukemia Research Institute is committed to the creation and ...

Trends in liver metastases at diagnosis among young adults with colorectal cancer: A SEER-based analysis, 2010–2022. Genotype-directed targeted therapy combined with HAIC and tislelizumab for ...

Spatial analyses uncovered how different tumor regions interact with immune cells and respond to therapies, offering a new ...