Recent advances in brain tumor classification have transformed neuropathological diagnostics in daily routine. Traditional diagnostic features, such as morphological appearance and single-protein ...

The composition and spatial organization of individual cells establish tissue structure and function. Advances in spatial transcriptomic technologies, which allow gene expression to be measured in a ...

In a recent study published in Nature Communications, a team of researchers at the Carl R. Woese Institute for Genomic Biology reports a new, robust computational toolset to extract biological ...

Foundation models (FMs), which are deep learning models pretrained on large-scale data and applied to diverse downstream tasks, have transformed natural language processing and multimodal AI. However, ...

Illumina's spatial transcriptomics offering is slated to provide analyses of millions of cells per experiment across a 50 mm by 15 mm imaging area. (Pixabay) Illumina is raising the curtain on its ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

Prevalence of germline variants of uncertain significance in DNA repair genes and their potential impact on prostate cancer outcomes following radical prostatectomy. This is an ASCO Meeting Abstract ...

Alliance A092104: A randomized phase 2/3 study of olaparib plus temozolomide versus investigator’s choice for the treatment of patients with advanced uterine leiomyosarcoma after progression on prior ...

Certain cells in the brain create a nurturing environment, enhancing the health and resilience of their neighbors, while others promote stress and damage. Using spatial transcriptomics and AI, ...

In a recent study published in the journal Nature, researchers developed spatial aging clocks using single-cell transcriptomics to explore cell-type-specific interactions and their impact on brain ...

A new spatial transcriptomic approach captures the regulation of splicing and polyadenylation sites during pubescent brain development at near-single-cell resolution. An international collaboration, ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...