Chloroplast gene expression is governed by a sophisticated network of nuclear‐ and plastid‐encoded factors that integrate transcription, RNA processing and translation. Central to this process is the ...
When a gene is expressed, its DNA sequence is transcribed into a molecule known as RNA. Then the cell processes and edits that RNA before it is translated into protein. Many genes can be processed and ...
A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other ...
A team of researchers from Mass General Brigham led by Raghu Chivukla, MD, PhD released a new study linking protein aggregation to altered RNA processing in genetic forms of neurodegeneration.
Different variants of a gene, known as isoforms, can be transcribed and translated at varying levels within a cell or tissue. These isoforms are commonly a result of alternative splicing, which ...
A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled “A ...
Advancing RNA therapeutics depends on understanding two critical questions: Where do drug candidates go, and what do they do ...
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Aging Alters RNA Splicing Networks Across the Human Body
Researchers analyzed gene expression and network connectivity across eight human tissues and found shared aging-related ...
Our results demonstrate that differential connectivity analysis reveals significant transcriptional alterations that are not ...
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