Retinitis pigmentosa (RP) is a genetic eye disorder affecting around one in 5,000 people worldwide. It typically begins with ...

The creation of memories in the brain involves addition or removal of methyl groups at precise spots on chromosomal DNA. But what controls the careful targeting of these neuronal DNA methylation ...

In patients with retinitis pigmentosa (RP), crucial cells in the retina known as rods and cones die over time; night ...

Understanding glioblastoma survival: A SEER-based study of demographics and treatment. Real-world experience with vorasidenib in IDH-mutant gliomas: Tolerability, adverse events, and access in ...

Universal rRNA depletion can put the power of RNA-seq at the disposal of researchers studying any organism, from dangerous pathogens to vital plant crops. The RNA sequencing (RNA-seq) revolution is ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

IOB researchers, in collaboration with a team from Radboud University Medical Center and partners from more than 100 institutions worldwide, identify new genetic cause of inherited blindness. The ...

Digital spatial profiling of advanced solid tumors and lymphomas from a phase 1 trial of copanlisib and nivolumab. Using single-cell sequencing to identify endothelial expression of immune checkpoint ...

A newly identified class of RNA molecules has been discovered in bacteria living inside the human body. These circular genetic structures, termed obelisks, differ from known viruses and bacteria and ...