Thrombocytopenia, inherited as a dominant trait, was present in three generations of a kindred. The clinical picture was quite similar to that of idiopathic thrombocytopenic purpura, but ...

A team from Würzburg has fundamentally changed our understanding of platelet biology. The researchers demonstrate that the ...

Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...

Platelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor ...

Thrombocytopenia absent radius (TAR) affects the radius — the long, thin bone in the forearm — and platelet function. This defect commonly appears at birth or within the first few years of life.

Study of the bleeding tendency in uremia in 26 subjects, 10 of whom were bleeding, showed platelet counts and plasma coagulation factors to be normal. There was a significant inverse correlation ...

Gut microbes alter platelet function and risk of blood clot-related illnesses like heart attack and stroke, researchers have demonstrated -- for the first time -- through a combination of both ...

Platelet function may aid in determining disease severity for patients with psoriasis who are at an increased risk of developing cardiovascular disease (CVD) and increased inflammation, a review notes ...

pills According to the investigators, nearly 25% of patients with CKD have MDD, and both conditions are independent risk factors for cardiovascular events. Treatment of major depressive disorder (MDD) ...