Scientists are learning how to interrupt pain before it forms

New research suggests pain is not a simple signal of injury but a process that unfolds across nerves, spinal cord, and brain.

Enzyme-blocking treatment reverses chronic pain in preclinical study

Chronic pain affects more than 50 million Americans, yet for decades, treatment options for pain that persists in the absence ...
Yahoo

How do painkillers actually kill pain? From ibuprofen to fentanyl, it’s about meeting the pain where it’s at

Add Yahoo as a preferred source to see more of our stories on Google. A variety of pain-relieving drugs are available both over the counter and by prescription. SelectStock/Vetta via Getty Images ...
KPBS

Pain pathway in a dish could aid search for new analgesic drugs

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...
GEN

Key Neural Pain-Sensing Pathway Recreated in a Lab Dish

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...
New Atlas

Pain-blocking parasite points to non-opioid painkillers

Around one million people every year suffer from a parasitic condition known as cutaneous leishmaniasis. Spread by sandfly bites, the parasite causes nasty skin ulcerations but for many people the ...
Smithsonian Magazine

Women Are More Likely to Have Irritable Bowel Syndrome. This Newfound Gut Pain Pathway Might Explain Why

Estrogen may cause certain colon cells, shown in green in this microscope image, to release a hormone called peptide YY. This, in turn, causes a different type of colon cell, colored magenta, to pump ...