The intracellular environment is highly compartmentalized; biomolecules (nucleic acids, proteins, lipids and so on) are spatiotemporally organized to form functional modules, signal pathways and ...

Peptide nucleic acids (PNAs) represent a revolutionary class of synthetic nucleic acid analogues, in which the traditional sugar–phosphate backbone is replaced by a neutral N-(2-aminoethyl) glycine ...

Nucleic acids are chains of nucleotides that are a vital part of all living beings. The two most common types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), which provide ...

Spherical nucleic acids (SNAs) can be used as potent drugs to effectively train the immune system to fight disease, by either boosting or dampening the immune response. By increasing the immune ...

内分泌信号，特别是雌激素信号，对维持两性哺乳动物的健康骨骼至关重要。成人雌激素信号缺乏的一个主要后果是破坏骨形成和吸收之间的平衡，吸收速度超过形成速度，导致净骨丢失，最终导致骨质疏松。 D1型肢带型肌营养不良症(LGMDD1)是由DNAJB6基因的主要 ...