Single nucleotide polymorphism (SNP) interaction plays a critical role for complex diseases. The primary limitation of logistic regressions (LR) in testing SNP–SNP interactions is that coefficient ...

多元自适应回归样条（Multivariate Adaptive Regression Splines, MARS）是Jerome Friedman于1991年提出的一种非参数回归技术。该方法专门用于建模预测变量集合与目标变量之间的复杂非线性关系，无需预先确定具体的函数形式。本文将深入探讨MARS算法的核心原理，并详细阐述 ...

The Annals of Statistics publishes research papers of the highest quality reflecting the many facets of contemporary statistics. Primary emphasis is placed on importance and originality, not on ...

This article considers methodology for hierarchical functional data analysis, motivated by studies of reproductive hormone profiles in the menstrual cycle. Current methods standardize the cycle ...