DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

Gene regulation and chromatin dynamics constitute central themes in modern molecular biology, governing how the genetic blueprint is accessed and utilised during development, differentiation and ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Until now, scientists had believed that ...

A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and ...

Researchers identify a shared RNA-protein interaction that could lead to broad-spectrum antiviral treatments for ...