Scientists have discovered that bacteria employ a type of DNA modification never before seen in nature. For several decades, researchers have known that it is possible to modify synthetic ...

CAMBRIDGE, MA -- DNA is made from four nucleosides, each known by its own letter -- A, G, C, and T. However, since the structure of DNA was deciphered in 1953, scientists have discovered several other ...

Figure 1: Dynamics of global levels of 5fC during mouse development are distinct from those of 5hmC. Tissues and cells were resuspended in lysis buffer (100 mM Tris, pH 5.5, 5 mM EDTA, 200 mM NaCl, ...

Collaborating researchers have made a breakthrough discovery regarding the intricate defense systems of bacteriophages (phages)—viruses that can specifically target harmful bacteria without harming ...

Scientists at the University of Chicago, Harvard, and China have described the surprising discovery and function of a new DNA modification in insects, worms, and algae. Common DNA modifications occur ...

Thomas W. van Ravesteyn, Marleen Dekker, Alexander Fish, Titia K. Sixma, Astrid Wolters, Rob J. Dekker, Hein P. J. te Riele Proceedings of the National Academy of Sciences of the United States of ...

Researchers Now Have the First Ever Tool to Detect Epigenetic and Other DNA Modifications Simultaneously within the Sequencing Workflow MENLO PARK, Calif.--Pacific Biosciences of California, Inc., ...

DNA is the basic building block of the genes that form the instructions to the cells on their birth, maturity, functions and eventually death. Understanding the chemistry of DNA is possibly the most ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

Scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) and collaborating institutions have developed a DNA-editing method that introduces small chemical modifications at ...

Researchers at The University of Queensland have discovered a DNA modification that enhances our ability to extinguish fear. The findings, published in the journal Nature Neuroscience, could help ...