The sugar-phosphate backbone forms the structural framework of nucleic acids, like DNA and RNA, and is composed of alternating sugar and phosphate groups.

32 P-label is introduced by incoming dGT 32 P molecule. The arrows indicate the sites of enzymatic hydrolysis. The bases of the template DNA strand are designated as clear boxes, and the bases in the ...

The DNA double helix is composed of two DNA molecules whose sequences are complementary to each other. The stability of the duplex can be fine-tuned in the lab by controlling the amount and location ...

The DNA double helix is composed of two DNA molecules whose sequences are complementary to each other. The stability of the duplex can be fine-tuned in the lab by controlling the amount and location ...

Researchers at Purdue's Birck Nanotechnology Center have shown how "nanopore channels" can be used to rapidly and precisely detect specific sequences of DNA as a potential tool for genomic ...

Researchers in China have developed a new method that allows them to insert long stretches of DNA into a genome. The process, named GRAND editing, is one of a handful of new systems aimed at using two ...

Carnegie Mellon University researchers have developed a synthetic molecule that can recognize and bind to double-stranded DNA or RNA under normal physiological conditions. The molecule could provide a ...

Using an atomic force microscope tip as a pen and different single-stranded DNA as inks, scientists at Northwestern University have demonstrated a technique that could lead to the ultimate ...

DNA is usually known as a biological carrier of information. However, scientists can use DNA as a building material to make microscopic structures. These DNA structures can self-assemble through ...

Chemists have made a discovery that supports a surprising new view of how life originated on our planet. They demonstrated that a simple compound called diamidophosphate (DAP), which was plausibly ...

Antisense oligonucleotides (ASOs) are small, single-stranded molecules that can suppress the expression of targeted genes and thereby achieve therapeutic effects. However, many ASO-based drug ...